摘要：
A novel organoantimony complex of 6-cyclohexyl-6,7-dihydrodibenzo[c,f] [1,5]azastibocin-12(5H)-yl nitrate (2) was synthesized and systematically characterized by techniques such as NMR spectra, TG-DSC, and X-ray diffraction. It was found that the complex 2 exhibits relatively strong Lewis acidity (3.3 < Ho ≤ 4.8) and could be employed as a water tolerant Lewis acid catalyst for the synthesis of synthetically valuable benzimidazole derivatives starting from aldehydes and arylenediamines. This catalytic system shows excellent tolerance toward a wide variety of functional groups, such as methyl, methoxyl, fluoro, chloro, bromo, nitro, cyan, trifluoromethyl, 1-naphthaldehyde, furfural and n-butyl, together with facile reusability in 5 times scale enlarged synthesis.
作者机构：
[Yongping Liu; Yi Chen; Kun Yu; Jian Lei; Chak-Tong Au; Shuang-Feng Yin] Medical College,Hunan University of Chinese Medicine;[Yongping Liu; Yi Chen; Kun Yu; Jian Lei; Chak-Tong Au; Shuang-Feng Yin] State Key Laboratory of Chemo/Biosensing and Chemometrics,College of Chemistry and Chemical Engineering,Provincial Hunan Key Laboratory for Cost-effective Utilization of Fossil Fuel Aimed at Reducing Carbon-dioxide Emissions,Hunan University;[Yongping Liu; Yi Chen; Kun Yu; Jian Lei; Chak-Tong Au; Shuang-Feng Yin] College of Chemistry and Chemical Engineering,Hunan Institute of Engineering
会议名称：
2016年国际生理学学术大会
会议时间：
2016-09-25
会议地点：
中国北京
摘要：
Based on the interaction mode between compounds and DNA,this study aimed to investigate the cytotoxic and apoptotic activity of two heterocyclic organobismuth compounds([O（CH2C6H4）2]BiCl: C1 and [
