作者机构：
[Cao L.] Key Laboratory of Chinese Materia Medica Modernization, Ministry of Education, Hunan University of Chinese Medicine, Changsha 410208, China;[卢向阳] School of Bioscience and Technology, Hunan Agricultural University, Changsha 410128, China;Key Laboratory of New Drug Research and Development of Chinese Materia Medica, Hunan Academy of Chinese Medicine, Changsha 410013, China;[李顺祥; 黄丹] Key Laboratory of Chinese Materia Medica Modernization, Ministry of Education, Hunan University of Chinese Medicine, Changsha 410208, China, Key Laboratory of New Drug Research and Development of Chinese Materia Medica, Hunan Academy of Chinese Medicine, Changsha 410013, China;[魏宝阳] Key Laboratory of Chinese Materia Medica Modernization, Ministry of Education, Hunan University of Chinese Medicine, Changsha 410208, China, School of Bioscience and Technology, Hunan Agricultural University, Changsha 410128, China
通讯机构：
[Li, S.-X.] K;Key Laboratory of Chinese Materia Medica Modernization, Ministry of Education, Hunan University of Chinese Medicine, China
作者机构：
[曹亮; 徐菲; 魏宝阳; 佟志远] Key Laboratory of Modernization of Chinese Materia Medica, College of Pharmacy, Hunan University of Traditional Chinese Medicine, Changsha 410208, China;[黄丹] Hunan Academy of Traditional Chinese Medicine, Changsha 410013, China;[李顺祥] Key Laboratory of Modernization of Chinese Materia Medica, College of Pharmacy, Hunan University of Traditional Chinese Medicine, Changsha 410208, China, Hunan Academy of Traditional Chinese Medicine, Changsha 410013, China
通讯机构：
[Cao, L.] K;Key Laboratory of Modernization of Chinese Materia Medica, College of Pharmacy, Hunan University of Traditional Chinese Medicine, China
作者机构：
[蔡萍; 张水寒; 袁清照] Key Laboratory of Chinese Materia Medica Research and Development, Hunan Academy of Chinese Medicine, Changsha 410013, China;Key Laboratory of Modernization of Chinese Medicine, Hunan University of Chinese Medicine, Changsha 410208, China;[李顺祥; 黄丹] Key Laboratory of Chinese Materia Medica Research and Development, Hunan Academy of Chinese Medicine, Changsha 410013, China, Key Laboratory of Modernization of Chinese Medicine, Hunan University of Chinese Medicine, Changsha 410208, China
通讯机构：
[Yuan, Q.-Z.] K;Key Laboratory of Chinese Materia Medica Research and Development, Hunan Academy of Chinese Medicine, China
作者机构：
[Huang, D.; Yue, C. H.; Li, S. X.] Hunan Acad Tradit Chinese Med, Hunan Prov Key Lab Drug Res, Changsha 410013, Peoples R China.;[Huang, D.; Yue, C. H.; Li, S. X.] Hunan Univ Tradit Chinese Med, Changsha 410007, Peoples R China.;[Long, M.; Li, S. X.; Zhang, Z. G.] Hunan Agr Univ, Changsha 410128, Peoples R China.;[Long, M.] SUNY Stony Brook, Stony Brook, NY 11794 USA.;[Zhang, Z. G.] Hunan Normal Univ, Changsha 410081, Peoples R China.
会议名称：
第九届全国中药和天然药物学术研讨会
会议时间：
2007-12-01
会议地点：
南昌
会议论文集名称：
第九届全国中药和天然药物学术研讨会论文集
关键词：
叶表面结构;骨碎补;柚皮苷;山奈酚;补肾成份
摘要：
OBJECTIVE：To study the kidney tonic components of Rhizoma Drynariae.METHODS：The herbal material was extracted with 50％ ethanol.Silica gel and sephadex LH-20 coluuln chromatography isolated the chemical components using the Opossurn Kidney cell for the living model.The structures were identified on the basis of chemical and spectroscopic data.RESULTS.Six monocases were isolated from the EtOH extract of in Rhizomes of Drynaria fortunei J.Sm..Four structures were identified as naringin(I)，neocriocitrin(Ⅱ)，kaempferol(Ⅲ)，and naringenin-7-O-β-D-glucoside(Ⅳ)，respectively，on the basis of its spectral and physicochemical evidence.The kaempferol call promote the proliferation of the Opossum Kidney cell tested by Promega’B CellTiter96 assay in vitr0.Others are in identifying.CONCLUSION：Compound In and IV are firstly isolated from this plant，and the later may hefurther developed into a new effective drug for treatingm rural failure.
