摘要：
The invention belongs to medical auxiliary instruments, and in particular to a moxa cone manufacturing device. The moxa cone manufacturing device comprises a moxa box and a forming die, wherein the forming die comprises at least two die blocks which are hinged at the top in sequence; a semi-forming hole is arranged on one side, close to the adjacent die block, of each die block; the semi-forming holes of every two adjacent die blocks are matched to form a forming hole; a cutting slot which transversely penetrates through the forming holes is arranged in the forming die; a cutting plate is slidably arranged in the cutting slot; notches which are consistent with the size of the penetrating side of the forming holes are arranged in the cutting plate. According to the invention, every two dieblocks form a forming hole which can be opened or closed, and a formed moxa cone is conveniently taken out, so that damage to the moxa cone is reduced to the greatest extent when the moxa cone is taken out; and through arrangement of the cutting slot and the cutting plate, after the die blocks are mutually closed in a forming process and the moxa cones are formed, the cutting plate can be drawn out to cut off the loose parts of the bottoms of the moxa cones, and meanwhile, smooth bottoms of the final moxa cones are ensured.
作者机构：
[Yongmei PENG; Ming XU; Guilan HUANG; Hong ZHANG; Kun AI] College of Acupuncture, Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha 410208, China (湖南中医药大学针灸推拿学院, 长沙 410208, 中国)
通讯机构：
[Hong ZHANG] C;College of Acupuncture, Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha 410208, China (湖南中医药大学针灸推拿学院, 长沙 410208, 中国)
摘要：
Objective:To investigate the effect and mechanism of electroacupuncture (EA) in the intervention of neurogenic bladder (NB) caused by suprasacral spinal cord injury (SCI). Methods:The total 60 female Sprague-Dawley (SD) rats were divided into blank group, sham operation group by adopting random number table method, with 12 rats in each group. The remaining rats were made into models through operation, and 24 successful model rats were randomly divided into model group and EA group, with 12 rats in each group. Since the 19th day after modeling, EA was conducted at "Ciliao"(次髎BL 32), "Zhongji" (中极CV 3), "Sanyinjiao"(三阴交SP 6) and "Dazhui"(大椎GV 14) in EA group, remaining the needle for 20 min every time. The intervention was performed for once a day, and 7 consecutive days were needed. The rest of the three groups were only tied up for the same time. Uro- dynamics test was conducted after the intervention. The contents of PACAP-38 and PAC1R of the spinal cord of the injury site were detected by Western blot. Results:Compared with the blank group, there were no significant differences in the bladder capacity, leak point pressure, bladder compliance and PACAP-38 and PAC1R contents in spinal cord in sham operation group; compared with the sham operation group, the maximum bladder capacity and the bladder compliance in the model group were lower (both P<0.05), the leak point pressure was higher (P<0.05), the contents of PACAP-38 and PAC1R were lower (both P<0.05); compared with the model group, the maximum bladder capacity and the bladder compliance in the EA group were higher (both P<0.05), the leak point pressure was lower (P<0.05), the contents of PACAP-38 and PAC1R were higher (both P<0.05). Conclusion:EA at BL 32, CV 3, SP 6 and GV 14 can improve the bladder function of NB rats of suprasacral SCI, and its mechanism may be related to the increase expression of PACAP-38 and PAC1R protein in the injured spinal cord tissue.
