通讯机构：
[Yan, Jie] H;Hunan Coll Tradit Chinese Med, Dept Acupuncture & Moxibust, Changsha 410007, Hunan, Peoples R China.
关键词：
Gastric mucosal injury/acupuncture effects;MMCSV;Relationship between Meridian and Viscus
摘要：
AIM: To explore the regularity of multi-meridians controlling a same viscus (MMCSV). METHODS: The rabbit gastric ulcer model was established by ethanol intragastric instillation. Fifty-six rabbits were randomly divided into normal group, model group (MG), model plus acupuncture at Foot Yangming Meridian group (YMG), model plus acupuncture at Foot Taiyin Meridian group (TYG), model plus acupuncture at Foot Shaoyang Meridian group (SYG), model plus acupuncture at Foot Jueyin Meridian group (JYG), model plus acupuncture at Foot Taiyang Meridian group (TYMG), with eight rabbits in each group. Gastric mucosal nitric oxide (NO) and nitric oxide synthase (NOS) were assayed by the nitric acid reductase method, and prostaglandin E2 (PGE2) and epidermal growth factor (EGF) were measured by radioimmunoassay. The comprehensive effects were analyzed by weighing method. RESULTS: Compared to MG, SYG, JYG and TYMG, the rabbits gastric mucosal injury index (GMII) reduced very significantly in YMG (P < 0.01). Compared to MG, the GMII also reduced significantly in TYG (P < 0.05). NO, NOS, PGE2 and EGF increased very significantly in YMG (P < 0.01). The EGF in YMG also increased significantly than that in TYG compared to those in MG, SYG, JYG and TYMG (P < 0.05). The PGE2 and EGF also increased very significantly in TYG than those in MG, JYG and TYMG (P < 0.01). While compared to SYG, the NOS increased significantly in TYG (P < 0.05). NOS was the highest in YMG (P < 0.01), and was higher in TYG than in MG (P < 0.01). CONCLUSION: MMCSV is common. The Foot Yangming Meridian is most closely related to the stomach, followed by Foot Taiyin Meridian, Foot Shaoyang Meridian and Foot Jueyin Meridian. Foot Taiyang Meridian has no correlation with the stomach. (C) 2005 The WJG Press and Elsevier Inc. All rights reserved.
作者机构：
[常小荣; 严洁; 岳增辉; 沈菁; 林亚平; 易受乡; 曹湘平] Dept. of Acupuncture and Moxibustion, Hunan Coll. Traditional Chinese Med., Changsha 410007 Hunan Province, China
通讯机构：
[Chang, X.-R.] D;Dept. of Acupuncture and Moxibustion, Hunan Coll. Traditional Chinese Med., China
关键词：
c-fos;nucleus of the solitary tract;acupuncture;facial acupoints;gastric distension
摘要：
Clinical practice has shown that acupuncture at facial acupoints has curative effects on some visceral diseases (especially gastrointestinal diseases). However, the physiological basis has not been clarified yet. In the present study, expression of c-fos in the nucleus of the solitary tract (NTS) of rats following gastric distension and electroacupuncture (EA) at Yangbai (GB14) and Sibai (ST2) as well as Jiache (ST6) acupoints was observed by using immunohistochemistry technique. After EA at the three facial acupoints, c-fos immunoreactive (c-fos-IR) neurons were mainly distributed in the medial (mNTS) and intermediate subnucleus of the NTS, and a few were scatteredly distributed in the dorsalmedial and commissural subnucleus of the NTS. Furthermore, there is difference in the number of c-fos-IR neurons in the mNTS following EA at the three facial acupoints. The number in the EA at ST2 and GB14 group is the highest and the lowest, respectively. Gastric distension induces obviously the expression of c-fos, which is mainly confined in the mNTS. The results suggest that the noxious visceral and somatic afferent information from the stomach and face may converge in the mNTS, which may be involved in the effect of EA at facial acupoints on the gastrointestinal pain.
作者机构：
Dept. of Acu-moxibustion and Massage, Hunan College of TCM, Changsha 410007,China
关键词：
香草;药物有效成分分离;灸术;免疫血清脂蛋白;高脂血症;兔;胆固醇
摘要：
Objective: To study the effect of medicinal herb-cake-separated moxibustion on serum lipoprotein levels in hyperlipemia rabbits. Methods: A total of 55 New-Zealand rabbits were randomly divided into control group (n=13), model group (n=14), direct moxibustion group (n=14) and medicinal herb-cake-separated moxibustion (indirect moxibustion) group (n=14). Hyperlipemia model was established by feeding the animals with specialized forage (15% vitellus powder, 5% lard, 0.5% cholesterol and common forage) for 6 weeks. Moxibustion was applied to “Juque”(CV 14), “Tianshu”(ST 25), “Fenglong”(ST 40), etc., 4 moxa-cones for every acupoint, once daily and continuously for 40 days. Serum triglyceride (TG) and total cholesterol (TCh) contents were assayed with colorimentric method. Results: Compared with control group, TCh and TG levels of model group increased significantly (P< 0.01). TCh and TG contents of direct moxibustion and indirect moxibustion groups were significantly lower than those of model group (P<0.01). Comparison between two moxibustion groups showed that serum TCh level of indirect moxibustion group was strikingly lower than that of direct moxibustion group (P<0.01). It indicated that both direct and indirect moxibustion could effectively lower hyperlipemia and the therapeutic effect of indirect moxibustion was significantly superior to that of direct moxibustion in lowering serum TCh level. Conclusion: Both direct and indirect moxibustion can regulate lipid metabolism and the therapeutic effect of medicinal herb-cake-separated moxibustion is superior to that of direction moxibustion in hyperlipemia rabbits.
