作者机构：
Hunan University of Chinese Medicine, Changsha, 410007;School of Medicine, Southeast University, Nanjing, 210009;Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, 410005;Brain Hospital of Hunan Province, Changsha, 410007;[Zhang Lin; Quan Shu-lin; Wang Jing-jing; Zhong Yan] Hunan University of Chinese Medicine, Changsha, 410007
通讯机构：
[Jing-jing Wang] H;Hunan University of Chinese Medicine, Changsha, China
摘要：
Objective: To observe the therapeutic efficacy of acupuncture plus Tai Ji Quan (Tai Chi) in recovering the neurological function and treating depression state in post-stroke depression patients, together with a 12-month follow-up. Methods: A total of 105 eligible post-stroke depression patients were randomized into an acupuncture plus Tai Ji group (53 cases) and a control group (52 cases) based on their visiting sequence. The patients all received routine treatment and rehabilitation training for stroke. In addition, the control group was given oral administration of citalopram hydrobromide tablets, 1 month as a course of treatment, for 3 courses in total. Meanwhile, the acupuncture plus Tai Ji group received acupuncture and practiced Tai Ji Quan, for 1 month and 12 months respectively. Before the intervention, after 1-month intervention and 12 months later, the National Institute of Health stroke scale (NIHSS), Barthel index (BI) and Hamilton depression rating scale (HAMD) were adopted for efficacy evaluation. Results: Prior to the intervention, there were no significant differences in HAMD, NIHSS and BI scores between the two groups (all P>0.05); after 1-month intervention, there were significant between-group differences in NIHSS, BI and HAMD scores (P<0.05 or P<0.01); the 12-month follow-up revealed significant between-group differences in NIHSS, BI and HAMD scores (all P<0.01). In the treatment of stroke, the total effective rate was 84.4 %in the acupuncture plus Tai Ji group, significantly higher than 68.9 %in the control group (P<0.05); in the treatment of depression, the total effective rate was 86.7 %in the acupuncture plus Tai Ji group, significantly higher than 77.8 %in the control group (P<0.05). Conclusion: Acupuncture plus Tai Ji Quan can produce a significant efficacy in improving the limb motor function and depression in post-stroke depression patients.
作者机构：
Hunan University of Chinese Medicine, Changsha, 410007;The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, 410005;Brain Hospital of Hunan Province, Changsha, 410007;[张林; 钟艳; 全淑林; 王净净] Hunan University of Chinese Medicine, Changsha, 410007;[石学慧] The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, 410005
通讯机构：
[Lin Zhang] H;Hunan University of Chinese Medicine, Changsha, China
关键词：
Acupuncture Therapy;Auricuar Point Sticking;Stroke;Complications;Heart Rate;Depression
摘要：
Objective: To investigate the effect of combining acupuncture and auricular point sticking on heart rate variability (HRV)in patients with post-stroke depression (PSD). Methods: A total of 80 cases with PSD were randomized into a treatment group and a control group. The control group was intervened by oral administration of paroxetine hydrochloride, whereas the treatment group received acupuncture plus auricular point sticking base on the same oral administration. The Hamilton depression rating scale (HAMD)and HRV were measured before and after treatment in both groups. Results: The individual and global scores of HAMD significantly dropped after 8 weeks of treatment in both groups (all P<0.05). In the treatment group, anxiety/somatization factor, sleep disturbance, hopelessness factor, cognition factor and global score were significantly different from those in the control group (all P<0.05). The 24 h standard deviation of all normal-to-normal R-R interval (SDNN), standard deviation of 5-minute average of normal R-R intervals (SDANN), root mean square of successive differences (RMSSD), percent of differences between adjacent normal R-R intervals >50 ms (PNN50)and high frequency (HF)were increased while low frequency (LF)and LF/HF decreased significantly after 8 weeks of treatment in both groups (P<0.05). All items in the treatment group were significantly different from those in the control group (all P<0.05). Conclusion: Combining acupuncture and auricular point sticking can enhance the conventional medical treatment for HRV in patients with PSD.
作者机构：
[全淑林; 钟艳; 王净净; 张林] Hunan University of CM, Changsha 410007, China;[刘叶辉; 石学慧] the Second Affiliated Hospital of Hunan University of CM;[李振光] Brain Hospital of Hunan Province
