作者机构:
[Qin, Li; Liu, Xin-min; Liao, Duan-fang; Tuo, Qin-hui; Shi, Zhe; Liao, DF] Hunan Univ Chinese Med, Key Lab Qual Evaluat Bulk Herbs Hunan Prov, Div Stem Cell Regulat & Applicat, Changsha 410208, Hunan, Peoples R China.;[Chen, Ying; Lin, Na; Zhu, Xiao-xin] China Acad Chinese Med Sci, Inst Chinese Mat Med, Beijing 100700, Peoples R China.;[Lu, Cong; Liu, Xin-min; Dong, Li-ming; Lv, Jing-wei] Chinese Acad Med Sci, Inst Med Plant Dev IMPLAD, Res Ctr Pharmacol & Toxicol, Beijing 100193, Peoples R China.;[Lu, Cong; Liu, Xin-min; Dong, Li-ming; Lv, Jing-wei] Peking Union Med Coll, Beijing 100193, Peoples R China.;[Bu, Lan-lan; Tuo, Qin-hui] Hunan Univ Chinese Med, Sch Med, Changsha 410208, Hunan, Peoples R China.
通讯机构:
[Zhu, XX ] C;[Liu, XM ; Liao, DF] H;Hunan Univ Chinese Med, Key Lab Qual Evaluat Bulk Herbs Hunan Prov, Div Stem Cell Regulat & Applicat, Changsha 410208, Hunan, Peoples R China.;China Acad Chinese Med Sci, Inst Chinese Mat Med, Beijing 100700, Peoples R China.;Chinese Acad Med Sci, Inst Med Plant Dev IMPLAD, Res Ctr Pharmacol & Toxicol, Beijing 100193, Peoples R China.
摘要:
Objective: To observe the effects of Conggan Zhixin Prescription (从肝治心组方 CGZXP) on myocardial ischemic of HGF protein expression and ischemic myocardial angiogenesis in rats. Methods: According to completely random method, SD rats were divided into 4 groups: sham-operated group, model group, Shexiang Baoxin pill (从肝治心组方 SXBXP) group and CGZXP group. Acute myocardial infarction animal models were induced by ligating the coronary artery, after model rats were made for 24 hours, giving them medicine 1 times per day. Rats were killed 14 days after modeling, the heart was removed, and cardiac conditions were observed by naked-eyes. Then use immunohistochemistry to determinate and detect angiogenesis and HGF protein expression of ischemic myocardial. Results: The expression of HGF of model group, CGZXP group and SXBXP group was higher than the sham-operated group (P〈0.05 or P〈0.01). And the expression of HGF of CGZXP group and SXBXP group was higher than the model group (P〈0.05). The expression of HGF of CGZXP group was higher than SXBXP group, but the difference was not statistically significant (P〉0.05). Conclusion: CGZXP can effectively increase the expression of HGF and promote neovascularization in ischemic myocardium, and protect ischemic myocardium.
摘要:
We investigated the processing of self-related information under the prime paradigm using event-related potentials (ERPs) to provide evidence for implicit self-positivity bias in Chinese individuals. Reaction times and ERPs were recorded when participants made positive/negative emotional judgments to personality-trait adjectives about themselves or others. Faster responses occurred to self-related positive adjectives and other-related negative adjectives, indicating implicit self-positivity bias at the behavioral level. ERPs showed an interaction between prime and emotion at the P300 amplitude, with larger P300 amplitudes for words within the self-positivity bias, indicating that self-related information occupied more attentional resources. Larger N400 amplitudes elicited by words that were inconsistent with the self-positivity bias, suggesting that accessing non-self-relevant information is more difficult than self-relevant information. Thus, P300 and N400 could be used as neuro-indexes of the implicit self-positivity bias.